Histone Deacetylases

Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.

Also Known As:

Histone Deacetylase; Class I Histone Deacetylases; Class II Histone Deacetylases; HDAC Proteins; Histone Deacetylase Complexes; Complexes, Histone Deacetylase; Deacetylase Complexes, Histone; Deacetylase, Histone; Deacetylases, Histone

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Amidohydrolases: 43
      - Histone Deacetylases: 5289

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Disease

Drug/Important Bio-Agent (IBA)